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Publications of Örjan Carlborg

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Reviews

de Koning, D.-J., Carlborg, Ö and Haley, C.S. The genetic dissection of immune response using gene-expression studies and genome mapping. 2005 105:343-352

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Carlborg Ö., and Haley, C.S. Opinion: Epistasis: too often neglected in complex trait studies? Nature Reviews Genetics. 2004 5: 618-625.

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QTL Mapping Methodology

Rönnegård, L., Mischenko, K., Holmgren, S. and Carlborg, Ö. Increasing the efficiency of VC QTL analysis by using reduced rank haplotype covariance matrices. Genetics 2007 176: 1935-1938

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Alvarez-Castro, J. and Carlborg, Ö. A general model for functional and statistical epistasis and its application in QTL analysis. Genetics 2007 176: 1151-1167

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Rönnegård, L. and Carlborg, Ö. Separation of base allele and sampling term effects gives new insights in variance component QTL analysis. BMC Genetics 2007, 8:1

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Gjuvsland, A., Hayes, B., Plahte, E., Omholt, S., Carlborg, Ö. Statistical epistasis is a generic feature of gene regulatory networks. Genetics 2007 175:.411-420

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Carlborg, Ö., De Koning, D.J., Manly, K.F., Chesler, E., Williams, R,W, & Haley, C.S. Methodological aspects of the genetic dissection of gene expression. Bioinformatics. 2005 21:2383-2393

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Ljungberg, K., Holmgren, S., and Carlborg, Ö. An optimisation algorithm for simultaneous search for multiple QTL. Bioinformatics 2004 20:1887-1895

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Ljungberg, K., Holmgren, S. and Carlborg, Ö. Efficient algorithms for Quantitative Trait Locus mapping problems. Journal of Computational Biology 2002 9:793-804.

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Carlborg, Ö. and Andersson, L. The use of randomization testing for detection of multiple epistatic QTL. Genetical Research 2002 79: 175-184.

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Carlborg, Ö., Andersson-Eklund, L., Andersson, L. Parallel computing in regression interval mapping. Journal of Heredity, 2001 92(5): 449-51.

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Carlborg, Ö., Andersson, L., Kinghorn, B. The use of a genetic algorithm for simultaneous mapping of multiple interacting quantitative trait loci. Genetics 2000 155: 2003-2010

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QTL Mapping Applied

Wright D, Butlin RK, Carlborg O. Epistatic regulation of behavioural and morphological traits in the zebrafish (Danio rerio). Behav Genet. 2006 Jun 3; [Epub ahead of print].

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Carlborg, Ö., Jacobsson, L., Åhgren, P., Siegel, P., Andersson, L. Epistatsis and the release of genetic variation in response to selection.Nature Genetics 2006 38:418-20.

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Carlborg, Ö., Brockmann, G.A., & Haley, C.S. Simultaneous mapping of epistatic QTL in DU6i x DBA/2 mice. Mammalian Genome. 2005 16:481-494.

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Keeling, L., Andersson, L., Schütz, K.E., Kerje, S., Fredriksson, R., Carlborg, Ö., Cornwallis, C.K., Pizzari, T. & Jensen, P. Chicken genomics - Plumage pigmentation and spiteful feather-pecking. Nature 2004 431: 645-646.

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Carlborg, Ö., Hocking, P., Burt, D. and Haley, C. Simultaneous mapping of epistatic QTL in chickens reveals clusters of QTL pairs with similar genetic effects on growth. Genetical Research 2004 83: 197-209.

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suppl

Kerje, S., Carlborg, Ö., Schutz, K., Jacobsson, L., Jensen, P. and Andersson, L. The Two-fold Difference in Adult Size between the Red Junglefowl and White Leghorn Chickens Is Largely Explained by a Limited Number of QTLs. Animal Genetics 2003 34:264-274.

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Schutz, K., Kerje, S., Jacobsson, L., Forkman, B., Carlborg, Ö., Andersson, L., Andersson, L., and Jensen, P. Major growth QTLs in fowl are related to fearful behavior – possible genetic links between fear responses and production traits in a red junglefowl x White Leghorn intercross. Behavioural Genetics 2004 34:121-130.

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Carlborg, Ö., Kerje, S., Schutz, K., Jacobsson, L., Jensen, P., and Andersson, L A Global Search Reveals Epistatic Interaction between QTLs for Early Growth in the Chicken. Genome Research 2003 13: 413-421.

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Schütz, K., Kerje, S., Carlborg, Ö., Jacobsson, L., Andersson, L. and Jensen, P. Analyses of a red junglefowl x White Leghorn intercross reveal trade-off in resource allocation between behaviour and production traits. Behavioural Genetics 2002 32: 423-433.

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Park, H.-B., Carlborg, Ö., Marklund, S., Andersson, L. Melanocortin-4 receptor (MC4R) genotypes have no major effect on fatness in a Large White x Wild Boar intercross. Animal Genetics 2002 33: 155-157

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Jeon J-T., Carlborg O, Tornsten A, Giuffra E, Amarger V, Chardon P, Andersson-Eklund L, Andersson K, Hansson I, Lundstrom K, Andersson L. A paternally expressed QTL affecting skeletal and cardiac muscle mass in pigs maps to the IGF2 locus. Nat Genet. 1999 21:157-158

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Others

Carlborg, Ö. New methods for mapping quantitative trait loci. PhD thesis, Acta Universitatis Agriculturae Sueciae, Veterinaria 121, Swedish University of Agricultural Sciences, 2002.

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Ljungberg, K., Holmgren, S., Carlborg, Ö. Efficient kernel algorithms for QTL mapping problems. Technical Report No. 2002-005, Department of Information Technology, Uppsala University.

 

Giuffra, E., Kijas, J. M. H., Amarger, V., Carlborg, Ö., Jeon, J.T., Andersson, L. The origin of the domestic pig: independent domestication and subsequent introgression. Genetics. 2000 154:1785-1791.

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Svensson, U.S.H., Sandström, R., Carlborg, Ö., Lennernäs, H. and Ashton, M. High In situ rat intestinal permeability of artemisinin unaffected by multiple dosing and with No evidence of P-glycoprotein involvement. Drug Metab Dispos. 1999 27:227-32.

 

Software

QTLFast – a computationally efficient software for mapping of single QTL and epistatic QTL pairs.

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Latest update: 06-07-28 08:56

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